HYDROPHILIC-HYDROPHOBIC COPOLYMER CARRYING SHORT-CHAIN FATTY ACID ESTER

[Object]To provide a derivative of a short chain fatty acid that can exhibit physiological functions inherent in the short chain fatty acid.[Solution]Provided is a block or graft copolymer including a hydrophobic segment of a repeat unit containing a short chain fatty acid ester that is hydrolyzable...

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Bibliographische Detailangaben
Hauptverfasser:	VONG, Binh Long, SHASHNI, Babita, NAGASAKI, Yukio, OKADA, Ryusaku, TAJIKA, Yuya, LEE, Yaroslav
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR CHEMICAL WORKING-UP
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Beschreibung
Zusammenfassung:	[Object]To provide a derivative of a short chain fatty acid that can exhibit physiological functions inherent in the short chain fatty acid.[Solution]Provided is a block or graft copolymer including a hydrophobic segment of a repeat unit containing a short chain fatty acid ester that is hydrolyzable by esterase in vivo and a hydrophilic segment including a poly(ethylene glycol) chain. These copolymers are effective in the treatment or therapeutic treatment of various diseases or disorders, including cancer.