ANTI-MGLUR5 ANTIBODIES AND USES THEREOF

ANTI-MGLUR5 ANTIBODIES AND USES THEREOF

This invention generally pertains to antibodies and antigen-binding antibody Fragments, preferably humanized, chimeric, and human antibodies and antigen-binding antibody fragments. compositions containing such antibodies and antigen-binding antibody fragments or cells, e.g., immune cells such as T,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SMITH, Jeffrey, T.L, BILLGREN, Jens J, SCALLEY-KIM, Michelle, MULLIGAN, Jenny, GARCIA-MARTINEZ, Leon, F, OJALA, Ethan Wayne, LOOMIS, Maria-Cristina, RAPORT, Carol, J, FAN, Pei, ALLISON, Daniel, S, LATHAM, John, A, DUTZAR, Benjamin, H, RUBIN, Vanessa Lisbeth
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:This invention generally pertains to antibodies and antigen-binding antibody Fragments, preferably humanized, chimeric, and human antibodies and antigen-binding antibody fragments. compositions containing such antibodies and antigen-binding antibody fragments or cells, e.g., immune cells such as T, Treg, or NK cells which express same, wherein such antibodies and antigen-binding antibody Fragments specifically bind to mGluR5. The invention also relates to therapeutic and diagnostic uses for the antibodies, antigen-binding antibody fragments, and compositions thereof.