RANKING BIOLOGICAL ENTITY PAIRS BY EVIDENCE LEVEL

A computer-implemented method of electronically mining medical and scientific datasets to determine a ranking indicating a level of evidence for an association between two entities is disclosed. The method comprises receiving a representation of an entity pair, performing first data mining on one or...

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Bibliographische Detailangaben
Hauptverfasser: LACOSTE, Alix Mary Benedicte, CHURCHER, Ian, SUTHERLAND, Russel David, NEIL, Daniel Lawrence, DE GIORGIO, Alexander, GAO, Yingkai
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A computer-implemented method of electronically mining medical and scientific datasets to determine a ranking indicating a level of evidence for an association between two entities is disclosed. The method comprises receiving a representation of an entity pair, performing first data mining on one or more unstructured datasets to generate one or more first scores each representing an extent of association between the entities of the entity pair, and performing second data mining on one or more structured datasets to generate one or more second scores each representing an extent of association between the entities of the entity pair. The method also comprises using a classifier to determine a predicted ranking for the entity pair using the one or more first scores and the one or more second scores, and providing the predicted ranking to a user as an indication of the strength of evidence for an association between the entities of the entity pair.