METHOD TO ISOLATE TCR GENES
The present disclosure provides methods to recover repertoires of T cell receptors (TCRs). In some embodiments, TCR repertoires are recovered from non-viable samples. In some embodiments, libraries of TCRαβ pairs are created. In some embodiments, the methods disclosed are used for cancer immunothera...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre ; ger |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KUILMAN, Thomas SCHUMACHER, Antonius, Nicolaas, Maria BENDLE, Gavin, M GADIOT, Jules, F.C GOMEZ-EERLAND, Raquel LINNEMANN, Carsten VAN HEIJST, Jeroen, W.J SCHRIKKEMA, Deborah, Sophie |
| description | The present disclosure provides methods to recover repertoires of T cell receptors (TCRs). In some embodiments, TCR repertoires are recovered from non-viable samples. In some embodiments, libraries of TCRαβ pairs are created. In some embodiments, the methods disclosed are used for cancer immunotherapy or diagnostic purposes. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_EP3999528A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>EP3999528A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_EP3999528A13</originalsourceid><addsrcrecordid>eNrjZJD2dQ3x8HdRCPFX8Az293EMcVUIcQ5ScHf1cw3mYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgHGlpaWpkYWjobGRCgBAAVtIBQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD TO ISOLATE TCR GENES</title><source>esp@cenet</source><creator>KUILMAN, Thomas ; SCHUMACHER, Antonius, Nicolaas, Maria ; BENDLE, Gavin, M ; GADIOT, Jules, F.C ; GOMEZ-EERLAND, Raquel ; LINNEMANN, Carsten ; VAN HEIJST, Jeroen, W.J ; SCHRIKKEMA, Deborah, Sophie</creator><creatorcontrib>KUILMAN, Thomas ; SCHUMACHER, Antonius, Nicolaas, Maria ; BENDLE, Gavin, M ; GADIOT, Jules, F.C ; GOMEZ-EERLAND, Raquel ; LINNEMANN, Carsten ; VAN HEIJST, Jeroen, W.J ; SCHRIKKEMA, Deborah, Sophie</creatorcontrib><description>The present disclosure provides methods to recover repertoires of T cell receptors (TCRs). In some embodiments, TCR repertoires are recovered from non-viable samples. In some embodiments, libraries of TCRαβ pairs are created. In some embodiments, the methods disclosed are used for cancer immunotherapy or diagnostic purposes.</description><language>eng ; fre ; ger</language><subject>ARTIFICIAL STONE ; BEER ; BIOCHEMISTRY ; CEMENTS ; CERAMICS ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDINGMATERIALS ; CONCRETE ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; LIME, MAGNESIA ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; REFRACTORIES ; SLAG ; SPIRITS ; TREATMENT OF NATURAL STONE ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220525&DB=EPODOC&CC=EP&NR=3999528A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220525&DB=EPODOC&CC=EP&NR=3999528A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KUILMAN, Thomas</creatorcontrib><creatorcontrib>SCHUMACHER, Antonius, Nicolaas, Maria</creatorcontrib><creatorcontrib>BENDLE, Gavin, M</creatorcontrib><creatorcontrib>GADIOT, Jules, F.C</creatorcontrib><creatorcontrib>GOMEZ-EERLAND, Raquel</creatorcontrib><creatorcontrib>LINNEMANN, Carsten</creatorcontrib><creatorcontrib>VAN HEIJST, Jeroen, W.J</creatorcontrib><creatorcontrib>SCHRIKKEMA, Deborah, Sophie</creatorcontrib><title>METHOD TO ISOLATE TCR GENES</title><description>The present disclosure provides methods to recover repertoires of T cell receptors (TCRs). In some embodiments, TCR repertoires are recovered from non-viable samples. In some embodiments, libraries of TCRαβ pairs are created. In some embodiments, the methods disclosed are used for cancer immunotherapy or diagnostic purposes.</description><subject>ARTIFICIAL STONE</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CEMENTS</subject><subject>CERAMICS</subject><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDINGMATERIALS</subject><subject>CONCRETE</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>LIME, MAGNESIA</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>REFRACTORIES</subject><subject>SLAG</subject><subject>SPIRITS</subject><subject>TREATMENT OF NATURAL STONE</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJD2dQ3x8HdRCPFX8Az293EMcVUIcQ5ScHf1cw3mYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXxrgHGlpaWpkYWjobGRCgBAAVtIBQ</recordid><startdate>20220525</startdate><enddate>20220525</enddate><creator>KUILMAN, Thomas</creator><creator>SCHUMACHER, Antonius, Nicolaas, Maria</creator><creator>BENDLE, Gavin, M</creator><creator>GADIOT, Jules, F.C</creator><creator>GOMEZ-EERLAND, Raquel</creator><creator>LINNEMANN, Carsten</creator><creator>VAN HEIJST, Jeroen, W.J</creator><creator>SCHRIKKEMA, Deborah, Sophie</creator><scope>EVB</scope></search><sort><creationdate>20220525</creationdate><title>METHOD TO ISOLATE TCR GENES</title><author>KUILMAN, Thomas ; SCHUMACHER, Antonius, Nicolaas, Maria ; BENDLE, Gavin, M ; GADIOT, Jules, F.C ; GOMEZ-EERLAND, Raquel ; LINNEMANN, Carsten ; VAN HEIJST, Jeroen, W.J ; SCHRIKKEMA, Deborah, Sophie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP3999528A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; ger</language><creationdate>2022</creationdate><topic>ARTIFICIAL STONE</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CEMENTS</topic><topic>CERAMICS</topic><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDINGMATERIALS</topic><topic>CONCRETE</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>LIME, MAGNESIA</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>REFRACTORIES</topic><topic>SLAG</topic><topic>SPIRITS</topic><topic>TREATMENT OF NATURAL STONE</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>KUILMAN, Thomas</creatorcontrib><creatorcontrib>SCHUMACHER, Antonius, Nicolaas, Maria</creatorcontrib><creatorcontrib>BENDLE, Gavin, M</creatorcontrib><creatorcontrib>GADIOT, Jules, F.C</creatorcontrib><creatorcontrib>GOMEZ-EERLAND, Raquel</creatorcontrib><creatorcontrib>LINNEMANN, Carsten</creatorcontrib><creatorcontrib>VAN HEIJST, Jeroen, W.J</creatorcontrib><creatorcontrib>SCHRIKKEMA, Deborah, Sophie</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KUILMAN, Thomas</au><au>SCHUMACHER, Antonius, Nicolaas, Maria</au><au>BENDLE, Gavin, M</au><au>GADIOT, Jules, F.C</au><au>GOMEZ-EERLAND, Raquel</au><au>LINNEMANN, Carsten</au><au>VAN HEIJST, Jeroen, W.J</au><au>SCHRIKKEMA, Deborah, Sophie</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD TO ISOLATE TCR GENES</title><date>2022-05-25</date><risdate>2022</risdate><abstract>The present disclosure provides methods to recover repertoires of T cell receptors (TCRs). In some embodiments, TCR repertoires are recovered from non-viable samples. In some embodiments, libraries of TCRαβ pairs are created. In some embodiments, the methods disclosed are used for cancer immunotherapy or diagnostic purposes.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre ; ger |
| recordid | cdi_epo_espacenet_EP3999528A1 |
| source | esp@cenet |
| subjects | ARTIFICIAL STONE BEER BIOCHEMISTRY CEMENTS CERAMICS CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDINGMATERIALS CONCRETE CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES LIME, MAGNESIA MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROCESSES OF PREPARING SUCH COMPOSITIONS REFRACTORIES SLAG SPIRITS TREATMENT OF NATURAL STONE VINEGAR WINE |
| title | METHOD TO ISOLATE TCR GENES |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T14%3A39%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KUILMAN,%20Thomas&rft.date=2022-05-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EEP3999528A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |