NRF2-ACTIVATING COMPOUND

NRF2-ACTIVATING COMPOUND

A compound having Nrf2-activating action is provided. The compound is represented by formula (I), a salt of the compound, or a solvate of the compound or salt:wherein R1a and R1b are identical or different and represent a hydrogen atom, an alkyl group, or a halogen atom; R2 represents an optionally...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: MIYABE, Tomoyo, MACHIDA, Shinnosuke, OBA, Yuka
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A compound having Nrf2-activating action is provided. The compound is represented by formula (I), a salt of the compound, or a solvate of the compound or salt:wherein R1a and R1b are identical or different and represent a hydrogen atom, an alkyl group, or a halogen atom; R2 represents an optionally substituted group derived from a heterocycle, and the heterocycle represents thiophene, furan, pyrrole, thiazole, or a fused ring including any of these heterocycles; R4 and R5 are identical or different and represent a hydrogen atom or an optionally substituted alkyl group, or R4 and R5 bind with each other to form -NH-CH=N-; R6 represents an optionally substituted alkyl group; A1, A2, A3, and A4 are identical or different and represent CH or N wherein the number of N is 1 or less; and Z represents a hydrogen atom or a halogen atom.