SMART TEMPERATURE-SENSITIVE HYDROGELS WITH ANTIFUNGAL PROPERTY THAT PERFORM CONTROLLED DRUG RELEASE

The present invention relates to temperature-sensitive smart hydrogels that feature antifungal property and perform controlled drug release. Smart hydrogels were developed to be used in the treatment of nail fungus. The inventive hydrogel formula comprises at least one natural polymer (polysaccharid...

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Bibliographische Detailangaben
Hauptverfasser: DUMAN, Osman, KANCI BOZOGLAN, Bahar, TUNC, Sibel
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to temperature-sensitive smart hydrogels that feature antifungal property and perform controlled drug release. Smart hydrogels were developed to be used in the treatment of nail fungus. The inventive hydrogel formula comprises at least one natural polymer (polysaccharide and/or protein) additive, at least one inorganic or organic additive, and an active pharmaceutical ingredient with antifungal property. The antifungal drug in hydrogel formulation is released in a controlled manner, and this not only shortens the treatment period but also reduces the amount of the drug administered since the necessity for regularly administering drugs to the fungal infection area is eliminated.