TABLETING OF SPECIFIC POLYMER STABILIZERS

The present disclosure relates to a method for manufacturing a tablet including(A) filling a starting material, which is in a solid form, in a first open cavity, which is formed by a first punch and a die, to obtain a second open cavity, which is filled at least partly with the starting material,(B)...

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Bibliographische Detailangaben
Hauptverfasser: SEIDEMANN, Lothar, RUCKDAESCHEL, Holger, GEOERG, Yean Yik, HERBST, Heinz, GFROERER, Thomas Georg, SATHYANARAYANA, Shyam Sundar
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present disclosure relates to a method for manufacturing a tablet including(A) filling a starting material, which is in a solid form, in a first open cavity, which is formed by a first punch and a die, to obtain a second open cavity, which is filled at least partly with the starting material,(B) closing the second open cavity by a second punch to obtain a first dosed cavity,(C) compressing the starting material at a compression temperature below 37° C. by moving at least one out of the first punch and the second punch to obtain a second closed cavity, which has a smaller volume than the first closed cavity, which results in formation of a trapped tablet of the starting material in the second closed cavity,(D) removing the trapped tablet to obtain the tablet, which has a tablet temperature below 37° C. directly after removal.