POROUS CELLULOSE MEDIUM AND METHOD FOR PRODUCING SAME

Provided is a novel porous cellulose medium that can efficiently separate a large target molecule in a calibration standard having a large pore diameter and a large pore volume and a weight average molecular weight from approximately 105.0 to 105.5. A porous cellulose medium including a porous cellu...

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Hauptverfasser: HIRABAYASHI, Yuki, SHIBATA, Toru, OKURA, Hiromichi
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided is a novel porous cellulose medium that can efficiently separate a large target molecule in a calibration standard having a large pore diameter and a large pore volume and a weight average molecular weight from approximately 105.0 to 105.5. A porous cellulose medium including a porous cellulose particle having a particle size from 1 to 600 µm, wherein, in sieving the porous cellulose medium for classification and using a fraction corresponding to aperture openings between 53 µm and 106 µm as a support for size exclusion chromatography, a polyethylene oxide standard is run through size exclusion chromatography with pure water as a mobile phase, and a weight average molecular weight Mw and a gel partition coefficient Kav of the polyethylene oxide standard satisfy Relationships (A) and (B) above:in a case where 4.80≤logMw≤5.50,Kav>−0.445×logMw+2.55in a case where 5.75≤logMw,0≤Kav