MACROPHAGE IMAGING AGENT

Composite particles, each of which is obtained by forming, on the surface of a gadolinium oxide-containing particle, a cover film that contains a polymer obtained by polymerizing a monomer component containing a monomer having an ethylenically unsaturated bond; a macrophage imaging agent which conta...

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Bibliographische Detailangaben
Hauptverfasser: KOSEKI, Hirokazu, TAMORI, Koji, MASUDA, Takeaki, KONDO, Teruyuki, KIMURA, Yu, TAKASE, Katsuyuki, MIYAJI, Masaaki, SON, Aoi, KAI, Hirokazu, MATSUDA, Tetsuya, IMAI, Hirohiko, AOKI, Tomohiro
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Composite particles, each of which is obtained by forming, on the surface of a gadolinium oxide-containing particle, a cover film that contains a polymer obtained by polymerizing a monomer component containing a monomer having an ethylenically unsaturated bond; a macrophage imaging agent which contains the composite particles; and a method for producing composite particles, wherein a monomer component containing a monomer having an ethylenically unsaturated bond and gadolinium oxide-containing particles are mixed with each other, and after emulsifying the thus-obtained monomer component-containing mixture in water in the presence of a surfactant and a polymerization initiator in water, the monomer component is polymerized, thereby forming cover films on the surfaces of the gadolinium oxide-containing particles.