ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS

ANTIBODY DRUG CONJUGATES HAVING LINKERS COMPRISING HYDROPHILIC GROUPS

Provided herein are linkers, linker-drug groups and anti-body-drug conjugates comprising hydrophilic groups.

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Bibliographische Detailangaben
Hauptverfasser: PALERMO, Mark, G, NAKAJIMA, Katsumasa, D'ALESSIO, Joseph, Anthony, MCNEILL, Eric, BURGER, Matthew, T, CHEN, Zhuoliang, YU, Bing, ZHANG, Qiang
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Provided herein are linkers, linker-drug groups and anti-body-drug conjugates comprising hydrophilic groups.