PCR METHOD AND KIT FOR DETERMINING PATHWAY ACTIVITY

The present invention relates to a method for designing primers and probes suitable for determining one or more cellular signaling pathway activities in a sample. In particular WNT, HH, AR, ER, PR, TGFbeta, NFkB, STAT1/2, STAT3, PI3K-F0X0, Notch and MAPK-AP1,and wherein the printers and probes ampli...

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Bibliographische Detailangaben
Hauptverfasser:	DEN BIEZEN, Eveline Catharina Anna Clasina, VAN STRIJP, Arnoldina Margaretha Wilhelmina, VAN BRUSSEL, Anne Godefrida Catharina, HOLTZER, Laurentius Henricus Franciscus Maria, WROBEL, Janneke
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a method for designing primers and probes suitable for determining one or more cellular signaling pathway activities in a sample. In particular WNT, HH, AR, ER, PR, TGFbeta, NFkB, STAT1/2, STAT3, PI3K-F0X0, Notch and MAPK-AP1,and wherein the printers and probes amplify and detect of the expression of three or more of the reference genes. The invention further relates to products comprising sets of primers and probes suitable for determining one or more cellular signaling pathway activity, and uses thereof.