COMPOSITIONS AND METHODS FOR PROTECTING EPITHELIAL AND BARRIER INTEGRITY

The inventions relate to the use of hemichannel blockers to modulate BRB integrity and function, RPE integrity and function, tight junction integrity and function, ZO-1 internalization, gap junction internalization, and/or type IV collagen levels in a subject.

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Bibliographische Detailangaben
Hauptverfasser: DUFT, Bradford James, GREEN, Colin Richard, MUGISHO, Odunayo Omolola Boluwarin
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The inventions relate to the use of hemichannel blockers to modulate BRB integrity and function, RPE integrity and function, tight junction integrity and function, ZO-1 internalization, gap junction internalization, and/or type IV collagen levels in a subject.