SYSTEM FOR MOLDING AND COATING OF PHARMACEUTICAL TABLETS

A coating extruder (100) for applying heat and pressure to melt and mix an active pharmaceutical ingredient and one or more excipients to produce a hot melt comprising a motion control unit (108) and an extrusion barrel (101), wherein the extrusion barrel (101) further comprises a primary inlet port...

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Bibliographische Detailangaben
Hauptverfasser: HALKUDE, Bhakti, TAKIZAWA, Bayan Teisho, GOODWIN, Evan James, CHATTOPADHYAY, Saptarshi, CASATI, Federica, MASCIA, Salvatore
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A coating extruder (100) for applying heat and pressure to melt and mix an active pharmaceutical ingredient and one or more excipients to produce a hot melt comprising a motion control unit (108) and an extrusion barrel (101), wherein the extrusion barrel (101) further comprises a primary inlet port (109), at least one temperature control block (102), a single or twin screw extruder (104), one or more secondary inlet ports (110), and a removable extrusion barrel liner (103) comprising openings aligned with said primary inlet port (109) and said one or more secondary inlet ports (110).