SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF

SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF

Activators of Kv3.1 and/or Kv3.2 channels which are therapeutically useful in the treatment of cognitive dysfunction and the negative symptoms which are associated with central nervous system disorders such as schizophrenia, Alzheimer's disease, Tourette's syndrome, autism, dementia, epile...

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Bibliographische Detailangaben
Hauptverfasser: CONTRERAS, Jean-Marie, MORICE, Christophe, MICHAUT-SIMON, Celine, TOOP, Hamish, GARRIDO, Fabrice, SINGH, Rajinder, SMITH, Erin, PAUL, Dharam, SCHAEFFER, Laurent, BAZZINI, Patrick, CHERY, Florence
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Activators of Kv3.1 and/or Kv3.2 channels which are therapeutically useful in the treatment of cognitive dysfunction and the negative symptoms which are associated with central nervous system disorders such as schizophrenia, Alzheimer's disease, Tourette's syndrome, autism, dementia, epilepsy and other disorders where gamma oscillations are dysfunctional are provided. The activators include substituted N-heteroaryl compounds.