METHOD FOR PREPARING BIOCOMPATIBLE POLYMER-BASED APIXABAN-LOADED MICROSPHERES

The present disclosure relates to a method for preparing biocompatible polymer-based Apixaban-loaded microspheres. More specifically, the present disclosure relates to a method for preparing biocompatible polymer-based Apixaban-loaded microspheres, where the method includes: i) adding a fatty acid o...

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Hauptverfasser: KIM, Ye-Ji, PARK, Jae Hyung, KIM, Mijung, LEE, Sang-Hwi, JEONG, Dooyong
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present disclosure relates to a method for preparing biocompatible polymer-based Apixaban-loaded microspheres. More specifically, the present disclosure relates to a method for preparing biocompatible polymer-based Apixaban-loaded microspheres, where the method includes: i) adding a fatty acid or triglyceride to a dispersed phase; and ii) preparing microspheres using a microfluidic method. The method for preparing biocompatible polymer-based Apixaban-loaded microspheres of the present disclosure may be effectively used in the preparation of microspheres in which Apixaban is stably encapsulated in high contents.