POLYPEPTIDES INHIBITING CD40L

The present invention relates to immunoglobulins that specifically bind CD40L and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides...

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Bibliographische Detailangaben
Hauptverfasser: Pattyn, Els, Beste, Gerald, Vlach, Jaromir, Sompel, Ariella Van de, Hsu, Jonathan, Buyse, Marie-Ange, Dewilde, Maarten, Meerts, Peter
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to immunoglobulins that specifically bind CD40L and more in particular to polypeptides, nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to compositions and in particular to pharmaceutical compositions that comprise such polypeptides, for prophylactic, therapeutic or diagnostic purposes. In particular, the immunoglobulins of the present invention inhibit the activity of CD40L and are safe.