SALT OF ALDOSE REDUCTASE INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF

SALT OF ALDOSE REDUCTASE INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF

The present invention provides a salt of an aldose reductase inhibitor represented by formula A-N. The salt can be prepared in a crystal form, which has significantly improved solubility relative to the compound of formula A, has low hygroscopicity and can exist stably, thus being easier to be forme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LI, Chunna, LIU, Xibao, LI, Pengfei, LIU, Xiaopeng, ZHOU, Caihong, WANG, Junling, YANG, Zhankun, YANG, Hanyu
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention provides a salt of an aldose reductase inhibitor represented by formula A-N. The salt can be prepared in a crystal form, which has significantly improved solubility relative to the compound of formula A, has low hygroscopicity and can exist stably, thus being easier to be formed into a medicament relative to the compound of formula A or other salts of the compound of formula A.