METHOD FOR IDENTIFYING EPITOPE ON PROTEIN

In one aspect, the present invention provides, for example, an improved method for identifying an epitope on a protein, comprising the following steps: (A) contacting a major histocompatibility complex (MHC molecule)-expressing cell differentiated from a stem cell or a progenitor cell derived theref...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: INOUE, Tomoaki, SEKIGUCHI, Nobuo, ITO, Shunsuke
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:In one aspect, the present invention provides, for example, an improved method for identifying an epitope on a protein, comprising the following steps: (A) contacting a major histocompatibility complex (MHC molecule)-expressing cell differentiated from a stem cell or a progenitor cell derived therefrom with a target protein; (B) isolating a complex of a peptide contained in the target protein and the MHC molecule from the MHC molecule-expressing cell; and (C) eluting the peptide from the complex and identifying the peptide.