METHODS OF SEPARATING LONG POLYNUCLEOTIDES FROM A COMPOSITION

One aspect of the invention provides a method of separating long polynucleotides from a composition. The method includes: introducing a composition including one or more long polynucleotides into a container including at least one boundary defined by a filter comprising a plurality of pores, wherein...

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Bibliographische Detailangaben
Hauptverfasser: SCHMITKE, Jennifer Louise, SARISOZEN, Can, LYNG, Robert John, GIBSON, Marcus Ian, PATIL, Vishwesh Ashok
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:One aspect of the invention provides a method of separating long polynucleotides from a composition. The method includes: introducing a composition including one or more long polynucleotides into a container including at least one boundary defined by a filter comprising a plurality of pores, wherein the pores have a smaller cross-sectional dimension than specified for the long polynucleotide's molecular weight; and applying elevated hydraulic pressure to the composition, thereby causing at least some of the one or more long polynucleotides to pass through the pores.