LATERAL FLOW ASSAY DEVICE FOR TRAUMATIC BRAIN INJURY DIAGNOSIS USING TIME-RESOLVED FLUORESCENCE ANALYSIS, AND METHOD FOR DIAGNOSING TRAUMATIC BRAIN INJURY BY USING SAME

Provided is a lateral flow assay device capable of detecting a traumatic brain injury marker including a sample pad into which a blood sample containing a traumatic brain injury marker is injected, an adsorption pad including a probe which is mixed to the marker when the traumatic brain injury marke...

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Bibliographische Detailangaben
Hauptverfasser: KIM, Hanshin, PARK, Jong-Myeon, KANG, Jongeun, HWANG, Kyu-Youn
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided is a lateral flow assay device capable of detecting a traumatic brain injury marker including a sample pad into which a blood sample containing a traumatic brain injury marker is injected, an adsorption pad including a probe which is mixed to the marker when the traumatic brain injury marker moves from the sample pad to form a traumatic brain injury marker complex, and a porous film which fluid-communicates with the adsorption pad and capillary-migrates the traumatic brain injury marker complex from the adsorption pad to a detection line, in which the probe includes a capture antibody consisting of an antibody labeled with a specific binding material specifically binding to the traumatic brain injury marker and a detector antibody consisting of an antibody labeled with a fluorescent material having a relatively long emission lifetime of 1 microsecond or more, and a mixture of at least two different kinds-origin antibodies is used as the antibody labeled with the specific binding material or the fluorescent material.