MODULAR ENDOSCOPIC SYSTEM FOR VISUALIZATION OF DISEASE

An endoscopic imaging device is disclosed. The device includes a body portion configured to be held in a user's hand and an endoscope portion configured to direct light onto a target. At least one excitation light source is configured to excite autofluorescence emissions of tissue cells and fluorescence emissions of induced porphyrins in tissue cells of the target. A white light source is configured to illuminate the surgical margin during white light imaging of the target. The device also includes an imaging sensor and a first optical filter configured to filter optical signals emitted by the target responsive to illumination with excitation light and permit passage of autofluorescence emissions of tissue cells and fluorescence emissions of the induced porphyrins in tissue cells to the imaging sensor. A second optical filter configured to filter optical signals emitted by the target responsive to illumination with white light and permit passage of white light emissions of tissues in the surgical margin to the imaging sensor. The endoscopic imaging device may be modular and comprise a base body portion that releasably receives, in an interchangeable fashion, one or more endoscopic optical housing portions.