TREATMENT OF FATTY LIVER DISEASE

The present invention relates to a method of treating fatty liver disease in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) 5′-N1N2N3N4N5N6-N7N8-dCm-dGc-N11N12N13N14N15N16-N17N18-3′. The fatty liver disease can be non-alcoholic fatty liver disease, such as simple fatty liver disease or NASH. The invention also relates to the use of adiponectin as a biomarker for identifying subjects more likely to respond to treatment with the compound on Formula (I) 5′-N1N2N3N4N5N6-N7N8-dCm-dGc-N11N12N13N14N15N16-N17N18-3′ and for assessing response of the subject during treatment with the compound of Formula (I) 5′-N1N2N3N4N5N6-N7N8-dCm-dGc-N11N12N13N14N15N16-N17N18-3′.