USE OF SIDEROMYCINS TO LIMIT CROSS-REACTIVITY AND IMPROVE BACTERIAL IDENTIFICATION IN ANTIBIOTIC SUSCEPTIBILITY ASSAYS

The present invention relates to the use of sideromycins as additives in non-replicative transduction particles based systems either to limit cross-reactivity of unwanted organisms or to identify the organism being run on an antibiotic susceptibility assay (AST assay). Addition of the sideromycins r...

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Bibliographische Detailangaben
Hauptverfasser: CHAN, Ryan, CADY, Kyle C
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to the use of sideromycins as additives in non-replicative transduction particles based systems either to limit cross-reactivity of unwanted organisms or to identify the organism being run on an antibiotic susceptibility assay (AST assay). Addition of the sideromycins removes or reduces light production from bacteria that are sensitive to them, allowing for prevention of cross-reactivity in AST assays and/or family, genus, and potentially species level bacteria strain identification when performing AST testing.