COMPOSITIONS FOR INHIBITING UBIQUITIN SPECIFIC PROTEASE 1

COMPOSITIONS FOR INHIBITING UBIQUITIN SPECIFIC PROTEASE 1

This disclosure relates to modulating ubiquitin specific protease 1 (USP1) and provides novel chemical compounds useful as inhibitors of USP1, as well as various uses of these compounds. USP1 inhibiting compounds are useful in the treatment of diseases and disorders associated with USP1, such as can...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIN, Jian, CARAVELLA, Justin Andrew, BUCKMELTER, Alexandre Joseph, FRITZEN, Edward L
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This disclosure relates to modulating ubiquitin specific protease 1 (USP1) and provides novel chemical compounds useful as inhibitors of USP1, as well as various uses of these compounds. USP1 inhibiting compounds are useful in the treatment of diseases and disorders associated with USP1, such as cancer.