METHODS FOR NUCLEIC ACID TARGET ENRICHMENT

The present disclosure provides, among other things, a way to amplify and sequence target sequences in a low-input sample. In some embodiments, the method comprises ligating a double-stranded adaptor onto a population of fragments to produce tagged fragments, and linearly amplifying the tagged fragm...

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Bibliographische Detailangaben
Hauptverfasser: PATEL, Kruti, EMERMAN, Amy, HENDRICKSON, Cynthia, BOWMAN, Sarah
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present disclosure provides, among other things, a way to amplify and sequence target sequences in a low-input sample. In some embodiments, the method comprises ligating a double-stranded adaptor onto a population of fragments to produce tagged fragments, and linearly amplifying the tagged fragments.