TUMOR-TARGETED AGONISTIC CD28 ANTIGEN BINDING MOLECULES

The present invention relates to tumor targeted bispecific agonistic antigen binding molecules characterized by monovalent binding to CD28, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same.

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Bibliographische Detailangaben
Hauptverfasser: SAM, Johannes, HOSSE, Ralf, GEORGES, Guy, HOFER, Thomas, KLEIN, Christian, UMAÑA, Pablo, MOESSNER, Ekkehard, GASSER, Stephan, FAUTI, Tanja, THOM, Jenny Tosca, VALLIER, Jean-Baptiste Pierre
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to tumor targeted bispecific agonistic antigen binding molecules characterized by monovalent binding to CD28, methods for their production, pharmaceutical compositions containing these antibodies, and methods of using the same.