COMPOSITIONS AND METHODS FOR TREATING ENDOMETRIOSIS

COMPOSITIONS AND METHODS FOR TREATING ENDOMETRIOSIS

Provided herein are peptides that bind β-catenin, and compositions comprising said peptides. Peptides binding β-catenin prevent translocation to the nucleus and modulate the canonical Wnt pathway. Also provided herein are methods of using said peptides and compositions in the treatment of tissue-inf...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HARDY, Amanda, BODDUPALLY, Keerthi, FIACCO, Stephen, ROSE, Tristin, PETROSSIAN, Tanya, WILLMORE, Matthew
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided herein are peptides that bind β-catenin, and compositions comprising said peptides. Peptides binding β-catenin prevent translocation to the nucleus and modulate the canonical Wnt pathway. Also provided herein are methods of using said peptides and compositions in the treatment of tissue-infiltrating conditions including endometriosis.