METHOD FOR PREPARING VIRUS-INFECTED CELL LINE AND ANIMAL MODEL

The present invention relates to a method for producing virus-infected cell line or animal model. According to the present invention, for a human-derived lipid layer of a virus, a bile acid or a bile acid derivative allows the lipid layer to be replaced with a target animal model-derived lipid layer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	LEE, Hong Jai, LEE, Sang Kyou, MOON, Jae Seung, KIM, Soo Ki, SHIN, Bo Young, SHIN, Jin Su
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FISHING FORESTRY HUMAN NECESSITIES HUNTING INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPIRITS TESTING TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a method for producing virus-infected cell line or animal model. According to the present invention, for a human-derived lipid layer of a virus, a bile acid or a bile acid derivative allows the lipid layer to be replaced with a target animal model-derived lipid layer; and this makes it possible to produce a virus-infected animal model that can be effectively used clinically without limitation resulting from species specificity. Furthermore, in the method for producing a cell line, viruses are mixed with a bile acid or a bile acid derivative and the mixture is used to treat a culture medium of a cell line, so that a cell line infected with a very high level of the viruses can be obtained. In addition, use of the method for producing a cell line of the present invention allows viruses to infect cell lines derived from various species and organs without limitation resulting from the viral species specificity and the restraining force related to the viral specific tissue or organ tropism.