DEEP EUTECTIC SOLVENT PLATFORM FOR ORAL PHARMACEUTICAL FORMULATIONS

The present invention relates to Eutectic Mixtures (EM), and preferably Deep Eutectic Solvents (DES), that are used in or as oral pharmaceutical formulation platforms. These platforms improve the solubility and bioavailability of active pharmaceutical ingredients (API), and especially of poorly wate...

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Bibliographische Detailangaben
Hauptverfasser: HODGINS, Niall, KLUFT, Bastiaan
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The present invention relates to Eutectic Mixtures (EM), and preferably Deep Eutectic Solvents (DES), that are used in or as oral pharmaceutical formulation platforms. These platforms improve the solubility and bioavailability of active pharmaceutical ingredients (API), and especially of poorly water-soluble APIs. The deep eutectic solvent (DES) compositions of the invention make use of a combination of a glycol with a polymer solubilizer component in specific molar ratios.