CRYSTALLINE FORMS OF MNK INHIBITORS

The present invention provides crystalline solids of 6′-((6-aminopyrimidin-4-yl)amino)-8′-methyl-2′H-spiro[cyclohexane-1,3′-imidazo[1,5-a]pyridine]-1′,5′-dione:The crystalline compounds of the present application are inhibitors of Mnk and finds utility in any number of therapeutic applications, incl...

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Bibliographische Detailangaben
Hauptverfasser: REICH, Siegfried, H, SPERRY, Samuel, BORER, Bennett, C, ERNST, Justin, T, SPRENGELER, Paul, A, WEBBER, Stephen, E, XIANG, Alan, X, WILSON, Jo Ann, Z
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides crystalline solids of 6′-((6-aminopyrimidin-4-yl)amino)-8′-methyl-2′H-spiro[cyclohexane-1,3′-imidazo[1,5-a]pyridine]-1′,5′-dione:The crystalline compounds of the present application are inhibitors of Mnk and finds utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.