METABOLITES OF [3-(4-{2-BUTYL-L-[4-(4-CHLORO-PHENOXY)-PHENYL]-LH-IMIDAZOL-4-YL } -PHEN OX Y)-PROP YL] -DIETHYL-AMINE

METABOLITES OF [3-(4-{2-BUTYL-L-[4-(4-CHLORO-PHENOXY)-PHENYL]-LH-IMIDAZOL-4-YL } -PHEN OX Y)-PROP YL] -DIETHYL-AMINE

The present invention relates to metabolites of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amine. These metabolites may act as RAGE antagonists. These metabolites may also be useful in assays to measure the presence or amount of one or more metabolites...

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Bibliographische Detailangaben
Hauptverfasser: VICTORY, Samuel, POLISETTI, Dharma Rao, GADDAM, Bapu, BANNER, William Kenneth, ANDREWS, Robert Carl
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:The present invention relates to metabolites of [3-(4-{2-butyl-1-[4-(4-chloro-phenoxy)-phenyl]-1H-imidazol-4-yl}-phenoxy)-propyl]-diethyl-amine. These metabolites may act as RAGE antagonists. These metabolites may also be useful in assays to measure the presence or amount of one or more metabolites of the parent compound in a sample.