METHOD FOR PRODUCING TARGET SUBSTANCE BY BACTERIAL FERMENTATION

The present invention provides a method for producing a target substance, the biosynthetic pathway of which is ATP-dependent, for example, amino acids, nucleosides, nucleotides, isoprenoids, and peptides, by fermentation of a bacterium which has been modified to overexpress a gene encoding a protein...

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Hauptverfasser: ZAKATAEVA Natalia, ANDRIANOVA Ekaterina, BABOSHIN Mikhail, SHUPLETSOV Mikhail, MALYKH Evgeniya, MASHKO Sergei, KHARCHENKO Maria, KRYLOV Aleksander, STOYNOVA Natalia, VOROSHILOVA Elvira, KOVALEVA Ekaterina, GOLUBEVA Lyubov
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides a method for producing a target substance, the biosynthetic pathway of which is ATP-dependent, for example, amino acids, nucleosides, nucleotides, isoprenoids, and peptides, by fermentation of a bacterium which has been modified to overexpress a gene encoding a protein having H+-translocating membrane-bound pyrophosphatase activity, for example, the hppA gene native to R. rubrum or a variant thereof.