CELL CULTURE BIOREACTOR

A cell culture bioreactor has perfusion membranes and gas transfer membranes or a gas phase in an extra-membrane space in contact with a film on the perfusion membranes. Gas transfer membranes may travel through the perfusion membranes or through the extra-membrane space. Examples with hollow fiber...

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Bibliographische Detailangaben
Hauptverfasser: LOGAN, Megan, PUNDSACK, Scott Raymond, AHMED, Moin, KILPATRICK, Shane Alexander Jaques
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:A cell culture bioreactor has perfusion membranes and gas transfer membranes or a gas phase in an extra-membrane space in contact with a film on the perfusion membranes. Gas transfer membranes may travel through the perfusion membranes or through the extra-membrane space. Examples with hollow fiber and flat sheet membranes are shown. One or more of the membranes optionally has a responsive surface, for example a thermo-responsive surface. In some examples, membranes are located in X-Y planes while the length of the reactor extends in a Z-direction.