IMPLANTABLE DEVICES FOR CELL THERAPY AND RELATED METHODS

Described herein are implantable devices comprising means for mitigating the foreign body response (FBR) and at least one cell-containing compartment which comprises a plurality of cells (e.g., live cells) encapsulated in a polymer composition comprising a cell-binding substance (CBS), as well as co...

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Bibliographische Detailangaben
Hauptverfasser:	BARNEY, Lauren, Emily, CARMONA, Guillaume, JOHNSTON, Erika Ellen, WOTTON, Paul Kevin, YIN, Zoe, HEIDEBRECHT, Richard, VEISEH, Omid, OBERLI, Matthias, Alexander, O'CONNOR, Owen, MILLER, Robert, James, SEWELL, Jared A, BEAUREGARD, Michael, PERITT, David, SMITH, Devyn McKinley, GONZALEZ, Francisco Caballero
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described herein are implantable devices comprising means for mitigating the foreign body response (FBR) and at least one cell-containing compartment which comprises a plurality of cells (e.g., live cells) encapsulated in a polymer composition comprising a cell-binding substance (CBS), as well as compositions and methods of making and using the same. The cells are capable of expressing a therapeutic agent useful for the treatment of a disease, disorder, or condition described herein.