PHARMACOGENOMIC SCREENING METHOD FOR ANTICIPATING A PATIENT'S RESPONSE TO THE TREATMENT OF OCULAR HYPERTENSION

The present invention discloses a method for in vitro screening of a patient's response to the treatment of ocular hypertension, comprising the steps of: (a) obtaining a sample of a biological fluid from a patient; and (b) determining the number of copies of an intronic portion of gene MLIP (ML...

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Hauptverfasser: CANUT JORDANA, Maria Isabel, BARRAQUER COMPTE, Rafael Ignacio, CASAROLI MARANO, Ricardo Pedro, ARMENGOL DULCET, Lluis, VILLA MARCOS, Olaya
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creator CANUT JORDANA, Maria Isabel
BARRAQUER COMPTE, Rafael Ignacio
CASAROLI MARANO, Ricardo Pedro
ARMENGOL DULCET, Lluis
VILLA MARCOS, Olaya
description The present invention discloses a method for in vitro screening of a patient's response to the treatment of ocular hypertension, comprising the steps of: (a) obtaining a sample of a biological fluid from a patient; and (b) determining the number of copies of an intronic portion of gene MLIP (MLIP-AS1), wherein more than one copy of said MLIP-AS1 is an indication that the patient is better responder to the treatment with prostaglandins, and wherein less than one copy of said MLIP-AS1 is an indication that the patient is responder to the treatment with β-blockers.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
VINEGAR
WINE
title PHARMACOGENOMIC SCREENING METHOD FOR ANTICIPATING A PATIENT'S RESPONSE TO THE TREATMENT OF OCULAR HYPERTENSION
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