PHARMACOGENOMIC SCREENING METHOD FOR ANTICIPATING A PATIENT'S RESPONSE TO THE TREATMENT OF OCULAR HYPERTENSION

The present invention discloses a method for in vitro screening of a patient's response to the treatment of ocular hypertension, comprising the steps of: (a) obtaining a sample of a biological fluid from a patient; and (b) determining the number of copies of an intronic portion of gene MLIP (ML...

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Bibliographische Detailangaben
Hauptverfasser:	CANUT JORDANA, Maria Isabel, BARRAQUER COMPTE, Rafael Ignacio, CASAROLI MARANO, Ricardo Pedro, ARMENGOL DULCET, Lluis, VILLA MARCOS, Olaya
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention discloses a method for in vitro screening of a patient's response to the treatment of ocular hypertension, comprising the steps of: (a) obtaining a sample of a biological fluid from a patient; and (b) determining the number of copies of an intronic portion of gene MLIP (MLIP-AS1), wherein more than one copy of said MLIP-AS1 is an indication that the patient is better responder to the treatment with prostaglandins, and wherein less than one copy of said MLIP-AS1 is an indication that the patient is responder to the treatment with β-blockers.