AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY

Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for t...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG, Jianhua, XU, Yuan, WU, Danyi, ZHAO, Haixia, LIU, Shengyang, SHANG, Ke, JIANG, Lei, XIE, Xiaoping, MAO, Xudong, SHOU, Jianyong, FENG, Zhiyong, DENG, Jianwen, ZHENG, Mingwei
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.