IMPROVED AND STABLE APREMILAST PHARMACEUTICAL COMPOSITIONS

The present invention relates to an improved and stable topical pharmaceutical compositions of apremilast used for the treatment of psoriasis and/or psoriatic arthritis. It further relates to processes of preparation of the stable compositions and the method of use for these compositions. The presen...

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Hauptverfasser: KALAKOTI, Srikanth, SREEDHARALA, Venkata Nookaraju
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creator KALAKOTI, Srikanth
SREEDHARALA, Venkata Nookaraju
description The present invention relates to an improved and stable topical pharmaceutical compositions of apremilast used for the treatment of psoriasis and/or psoriatic arthritis. It further relates to processes of preparation of the stable compositions and the method of use for these compositions. The present invention provides a topical composition of Apremilast with improved and enhanced diffusion rate over prior art Apremilast topical compositions and also provides a drug diffusion form the topical composition at a lower strength which is equal to or better than a higher strength conventional composition of Apremilast.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title IMPROVED AND STABLE APREMILAST PHARMACEUTICAL COMPOSITIONS
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