IMPROVED AND STABLE APREMILAST PHARMACEUTICAL COMPOSITIONS

The present invention relates to an improved and stable topical pharmaceutical compositions of apremilast used for the treatment of psoriasis and/or psoriatic arthritis. It further relates to processes of preparation of the stable compositions and the method of use for these compositions. The presen...

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Bibliographische Detailangaben
Hauptverfasser:	KALAKOTI, Srikanth, SREEDHARALA, Venkata Nookaraju
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to an improved and stable topical pharmaceutical compositions of apremilast used for the treatment of psoriasis and/or psoriatic arthritis. It further relates to processes of preparation of the stable compositions and the method of use for these compositions. The present invention provides a topical composition of Apremilast with improved and enhanced diffusion rate over prior art Apremilast topical compositions and also provides a drug diffusion form the topical composition at a lower strength which is equal to or better than a higher strength conventional composition of Apremilast.