IMMUNOGLOBULIN-BINDING PROTEIN, AND AFFINITY CARRIER USING SAME

Provided is an affinity carrier having improved alkali resistance. Also provided is an immunoglobulin-binding protein containing a mutant polypeptide chain, as well as an affinity carrier containing a solid-phase carrier to which the immunoglobulin-binding protein is bound. The mutant polypeptide ch...

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Bibliographische Detailangaben
Hauptverfasser: ICHII, Takashi, HONDA, Toshinari, HAGA, Tomoaki, ONOGI, Shunsuke, KAMIDE, Tomoyuki, NAKAMURA, Satoshi
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Provided is an affinity carrier having improved alkali resistance. Also provided is an immunoglobulin-binding protein containing a mutant polypeptide chain, as well as an affinity carrier containing a solid-phase carrier to which the immunoglobulin-binding protein is bound. The mutant polypeptide chain has an amino acid sequence having at least 85% identity to an amino acid sequence indicated by any of SEQ ID NO: 1-6 and 57-62 and having a predetermined mutation, and has immunoglobulin-binding activity.