MODIFIED BIOTIN, STREPTAVIDIN MUTANT, AND USAGE OF THEM

An object of this invention is to provide a streptavidin mutant reduced in affinity to the naturally-occurring biotin, and to provide a modified biotin which shows a high affinity to such streptavidin mutant reduced in affinity to the naturally-occurring biotin. This invention can provide a compound...

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Hauptverfasser: KODAMA, Tatsuhiko, MESHIZUKA, Tomohiro, DOI, Hirofumi, INOUE, Tsuyoshi, SUGIYAMA, Akira, KAWATO, Tatsuya, SHIMIZU, Yohei, MIZOHATA, Eiichi, KANAI, Motomu, TAKASU, Noriaki, TAKATSU, Mari
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:An object of this invention is to provide a streptavidin mutant reduced in affinity to the naturally-occurring biotin, and to provide a modified biotin which shows a high affinity to such streptavidin mutant reduced in affinity to the naturally-occurring biotin. This invention can provide a compound composed of a dimer of modified biotin, a streptavidin mutant, angsd usage of them.