CHLORINATED DERIVATIVE OF HYALURONIC ACID, METHOD OF PREPARATION THEREOF, A COMPOSITION CONTAINING THE DERIVATIVE, AND USE THEREOF

A chlorinated derivative of hyaluronic acid or of a modified hyaluronic acid (chloramide) is provided. The chloramide has an amidic group (-NH-CO-). The hydrogen of the amidic group is substituted by a chlorine atom, according to the structural formula -NCl-CO-. The substitution degree of the hyalur...

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Hauptverfasser: PITUCHA, Tomas, SOBOTKA, Lubos, VELEBNY, Vladimir, SOJKA, Martin, KREJCI, Helena, CHLADKOVA, Drahomira, KNOTKOVA, Katerina, HERMANNOVA, Martina, BASARABOVA, Ivana, CHMELAR, Josef, KULHANEK, Jaromir, VAGNEROVA, Hana, BUFFA, Radovan
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A chlorinated derivative of hyaluronic acid or of a modified hyaluronic acid (chloramide) is provided. The chloramide has an amidic group (-NH-CO-). The hydrogen of the amidic group is substituted by a chlorine atom, according to the structural formula -NCl-CO-. The substitution degree of the hyaluronic acid or of the modified hyaluronic acid by chlorine is in an amount of from 50 to 100 %.