METHODS OF TREATING LIVER DISEASES

METHODS OF TREATING LIVER DISEASES

Provided herein are methods and compositions for the treating a patient with one or more conditions associated with PNPLA3, such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and/or alcoholic liver disease (ALD). Methods and compositions are also provided for modu...

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Bibliographische Detailangaben
Hauptverfasser: SMITH, Cynthia, Marie, GAMBOA, Mario, Esteban Contreras, SCHWARTZ, Brian, Elliott, SEHGAL, Alfica, GROSSMAN, Iris, WHISSELL, Gavin, SIGOVA, Alla, BUMCROT, David, A, RAJAGOPAL, Vaishnavi
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Provided herein are methods and compositions for the treating a patient with one or more conditions associated with PNPLA3, such as nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and/or alcoholic liver disease (ALD). Methods and compositions are also provided for modulating the expression of the PNPLA3 gene in a cell by altering gene signaling networks. Companion diagnostic methods, compositions and kits are also provided.