FORMULATIONS FOR IMPROVED STABILITY OF RECOMBINANT HUMAN PARATHYROID HORMONE

The invention relates to pharmaceutical compositions and dosage forms comprising full-length recombinant human parathyroid hormone (rhPTH(1-84)). The invention further relates to new and/or improved PTH compositions having improved in-use stability that are resistant to protein degradation in respon...

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Bibliographische Detailangaben
Hauptverfasser:	DIXIT, Nitin, NGUYEN, Vinh, BASU, Sujit, SOUILLAC, Pierre
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to pharmaceutical compositions and dosage forms comprising full-length recombinant human parathyroid hormone (rhPTH(1-84)). The invention further relates to new and/or improved PTH compositions having improved in-use stability that are resistant to protein degradation in response to physical and chemical stresses.