SOLID DISPERSION COMPRISING AN ANTICANCER COMPOUND WITH IMPROVED SOLUBILITY AND EFFICACY

The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound...

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Bibliographische Detailangaben
Hauptverfasser:	VISHWAKARMA, Ram, MINTOO, Mubashir Javed, BHARATE, Sonali Sandip, BHARATE, Sandip Bibishan, MONDHE, Dilip Manikrao, KUMAR, Vikas
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention is related to the novel solid dispersion formulations of an anticancer compound of formula A and a process for preparing the same wherein the anticancer compound is formulated with hydrophilic polymer. The said formulation showed enhanced dissolution of the anticancer compound and improved in-vivo anticancer activity. The said formulations are useful for the treatment of various types of cancer.