METHOD FOR PRODUCING HUMAN A1 ASTROCYTES, HUMAN A1 ASTROCYTES, AND METHOD FOR EVALUATING TEST SUBSTANCE

The present invention provides a method for producing human A1 astrocytes, which includes inducing human A1 astrocytes from human astrocytes other than human A1 astrocytes; human A1 astrocytes obtained by the method for producing human A1 astrocytes; and a method for evaluating a test substance, whi...

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Hauptverfasser: ENDOH Setsu, SHIN Wigyon, KOBAYASHI Hayato, NABETANI Akira
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The present invention provides a method for producing human A1 astrocytes, which includes inducing human A1 astrocytes from human astrocytes other than human A1 astrocytes; human A1 astrocytes obtained by the method for producing human A1 astrocytes; and a method for evaluating a test substance, which uses the human A1 astrocytes described above. According to the present invention, there is provided the method for producing human A1 astrocytes, which includes a step a of culturing human astrocytes other than human A1 astrocytes in the presence of TNFα and IFNγ.