NUCLEIC ACID FOR TREATING CRUSTACEAN ALLERGY

[Problem] To provide a nucleic acid expected to be useful in treating crustacean allergy. [Solution] Provided is a nucleic acid including, in the following order: a base sequence that encodes a signal peptide; a base sequence that encodes a LAMP intra-organelle stabilizing domain; a base sequence th...

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1. Verfasser: MARUI, Takanori
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:[Problem] To provide a nucleic acid expected to be useful in treating crustacean allergy. [Solution] Provided is a nucleic acid including, in the following order: a base sequence that encodes a signal peptide; a base sequence that encodes a LAMP intra-organelle stabilizing domain; a base sequence that encodes an allergen domain including Litv1, Litv4, and Litv3; a base sequence that encodes a transmembrane domain; and a base sequence that encodes a LAMP endosomal/lysosomal targeting domain, wherein the nucleic acid includes a base sequence that encodes a chimeric protein.