BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF

BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF

Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antag...

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Bibliographische Detailangaben
Hauptverfasser: CHEN, Austin Chih-Yu, OBALLA, Renata Marcella, BRAVO, Yalda, POWELL, David Andrew, LAM, Heather, NAGAMIZO, Joe Fred, DING, Jinyue, GOMEZ, Robert, SHENG, Tao
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.