HYDROGEL CAPSULE

The purpose of the present invention is to provide means for removing highly proliferative Ki67-positive cells that co-exist with differentiation-induced insulin-secreting cells. This method is for producing an insulin-producing cell population or a pancreatic beta cell population containing less th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TOYODA, Taro, UENO, Hikaru, KOIKE, Yusuke, KIMOTO, Koya, TANOUE, Yutaka, MOCHIDA, Taisuke, ITO, Ryo
Format: Patent
Sprache:eng ; fre ; ger
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Beschreibung
Zusammenfassung:The purpose of the present invention is to provide means for removing highly proliferative Ki67-positive cells that co-exist with differentiation-induced insulin-secreting cells. This method is for producing an insulin-producing cell population or a pancreatic beta cell population containing less than 3% of Ki67-positive cells, comprising embedding of an endocrine progenitor cell population or a cell population at a later differentiation stage in a gel containing alginic acid for further differentiation.