AZACYANINE DYES AND USE THEREOF

The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bi...

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Hauptverfasser: MORALES MORALES, Alma Rosa, SINGH, Rajendra, GOUN, Elena, A, SINISI, Riccardo
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bioconjugates for in-vitro and in-vivo assays and fluorescence imaging.